http://www.ovariancancerlive.com Just another WordPress weblog Tue, 03 Jun 2008 16:55:14 +0000 http://backend.userland.com/rss092 en Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness Paul P. Szotek*, Rafael Pieretti-Vanmarcke*, Peter T. Masiakos*, Daniela M. Dinulescu, Denise Connolly, Rosemary Foster, David Dombkowski¶, Frederic Preffer¶, David T. MacLaughlin*, and Patricia K. Donahoe*,|| *Pediatric Surgical Research Laboratories, Department of Surgery, and ¶Flow ... http://www.ovariancancerlive.com/2008/06/03/definition-of-cells/ Troglitazone (TGZ) is a potential anticancer agent. Little is known about the effect of this agent on cancer cell migration. Methods Human ovarian carcinoma cell line, ES-2 cells were treated with various concentrations of TGZ. Cell migration was evaluated by wound-healing and Boyden chamber transwell experiments. PPAR gamma expression was blocked by ... http://www.ovariancancerlive.com/2008/06/03/background-2/ A new study published in CANCER found that cigarette smoking and alcohol consumption do increase ovarian cancer risk while caffeine may lower the risk, particularly in women not using hormones. Various studies have assessed the potential link between modifiable factors such as smoking or caffeine and alcohol intake and have generated ... http://www.ovariancancerlive.com/2008/06/03/caffeine-reduces-ovarian-cancer-risk-alcohol-and-smoking-no-effect/ Advocates and researchers at the University of Michigan hope that increased awareness about ovarian cancer can save lives. Here is what they want you to know. Symptoms do exist. Bloating, pelvic or abdominal pain, difficulty eating, feeling full quickly, and frequent or urgent urinating are have been shown to be related ... http://www.ovariancancerlive.com/2008/06/03/ovarian-cancer-6/ Ko-Hui Tung1, Marc T. Goodman1 , Anna H. Wu2, Katharine McDuffie1, Lynne R. Wilkens1, Laurence N. Kolonel1, Abraham M. Y. Nomura1, Keith Y. Terada3, Michael E. Carney3 and Leslie H. Sobin4 1 Cancer Etiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI. 2 Norris Comprehensive Cancer Center, University of ... http://www.ovariancancerlive.com/2008/06/03/reproductive-factors-and-epithelial-ovarian-cancer-risk-by-histologic-typea-multiethnic-case-control-study/ One reason that ovarian cancer is such a deadly disease is because it is not usually diagnosed until it has reached an advanced stage. In this study, we developed a novel algorithm for group biomarkers identification using gene expression data. Group biomarkers consist of coregulated genes across normal and different ... http://www.ovariancancerlive.com/2008/06/03/ovarian-cancer-5/ Background Ovarian cancer is a devastating disease partly because conventional chemotherapy ignores aspects of tumour biology. Recurrence represents the "true killer" among ovarian cancer patients and identification of novel molecular markers present in recurrent tumours is urgently required. We carried out gene expression profiling between primary and recurrent ovarian cancers and ... http://www.ovariancancerlive.com/2008/06/03/an-integrative-model-for-recurrence-in-ovarian-cancer/ Symptoms Ovarian cancer does not cause many symptoms in its early stages. This is why 75% to 80% of cases are not found until the cancer has spread. 2 Most women do have symptoms in the 6 to 12 months before ovarian cancer is found. Symptoms that occur in later stages ... http://www.ovariancancerlive.com/2008/06/03/ovarian-cancer-4/ Background Standard chemotherapy for newly diagnosed ovarian cancer is a platinum–taxane combination. The Gynecologic Oncology Group conducted a randomized, phase 3 trial that compared intravenous paclitaxel plus cisplatin with intravenous paclitaxel plus intraperitoneal cisplatin and paclitaxel in patients with stage III ovarian cancer. Methods We randomly assigned patients with stage ... http://www.ovariancancerlive.com/2008/06/03/ovarian-cancer-3/ Use of oral contraceptives during a woman's life-time gives substantial long-term protection against ovarian cancer - and the longer they are used, the greater the reduction in risk. These are the conclusions of authors of an Article in this week's edition of The Lancet. Use of oral contraceptives has long been ... http://www.ovariancancerlive.com/2008/06/03/oral-contraceptives-give-substantial-long-term-protection-against-ovarian-cancer/